Science

Examining self-belief formation through artificial beliefs

Abstract Psychological research has addressed key questions about self-beliefs, such as when they are formed, how they are shaped, or what functions they might have. The fundamental question of how we arrive at these self-beliefs in the first place has mostly been neglected, and there is currently no mechanistic description of the underlying processes. While […]

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Neurocomputational mechanisms underlying maladaptive self-belief formation in depression

Abstract A core symptom of major depression is maladaptive self-beliefs. These are perpetuated by negatively biased feedback processing. Understanding the neurocomputational mechanisms of biased belief updating may help to counteract maladaptive beliefs. The present study uses functional neuroimaging to examine neural activity associated with prediction error-based learning in depression and healthy controls. We hypothesized that

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Altered physiological, affective, and functional connectivity responses to acute stress in patients with alcohol use disorder

Abstract Background There is evidence that the processing of acute stress is altered in alcohol use disorder (AUD), but little is known about how this is manifested simultaneously across different stress parameters and which neural processes are involved. The present study examined physiological and affective responses to stress and functional connectivity in AUD. Methods Salivary

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The Human Affectome

Abstract Over the last decades, the interdisciplinary field of the affective sciences has seen proliferation rather than integration of theoretical perspectives. This is due to differences in metaphysical and mechanistic assumptions about human affective phenomena (what they are and how they work) which, shaped by academic motivations and values, have determined the affective constructs and

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Rethink funding!? New paper and Shiny App published

Rethink funding!? Every funding agency, be it the German (DFG), Swiss (SNF), British (Wellcome Trust), US American (NIH), Chinese (NSFC), or French (ANR) research foundation, has its own scheme on how to allocate research funding to the researchers. And research funding determines what is considered good science, it controls future science, and it shapes future knowledge.  However, meta-science research increasingly shows that funding allocation is inherently

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How do we arrive at our beliefs? “Neurocomputational mechanisms of affected beliefs” out now!

Affected beliefs Researchers at Lübeck University show links between emotions and the formation of self-efficacy beliefs   Why do some people believe that they are good at something and others not, while performing exactly similar? A recent study from Lübeck University, Germany, finds that emotional experiences are linked to the way people establish novel beliefs

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Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders

New publication with contribution by Annalina V. Mayer! Abstract This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain Criteria (RDoC) framework in a large transnosological population which cuts

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New publication out! Association of stress-related neural activity and baseline interleukin-6 plasma levels in healthy adults

Phantastic news! The first paper as part of the PhD by Johanna Voges is finally published! In this paper we assessed the link between baseline plasma levels of the cytokine interleukin (IL)-6 and neural markers of psychosocial stress. Using the Montreal Imaging Stress Task (MIST) we scanned 65 healthy individuals and found a negative association

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New publication out in Human Brain Mapping!

“Age-related topographic map of magnetic resonance diffusion metrics in neonatal brains” by Pratheek S. Bobba, Clara F. Weber et al., 2022 Very cool new publication by our PhD student Clara F. Weber! Congratulations!   Bobba, P. S., Weber, C. F., Mak, A., Mozayan, A., Malhotra, A., Sheth, K. N., Taylor, S. N., Vossough, A., Grant, P. E., Scheinost, D., Constable, R. T., Ment, L. R., & Payabvash, S. (2022). Age-related

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Determinants of motivated behavior are linked to fatigue and its perturbation by SARS-CoV-2 vaccination

New preprint out! In this very collaborative research project, we assessed the impact of a SARS-CoV-2 vaccination on determinants of motivated behavior: mental and physical exhaustion. To do so, we made use of a novel experimental paradigm (developed and extensively piloted by first author David S. Stolz), the Learn/Effort-task, to quantify these sub-facets of motivated

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