2022

Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders

Abstract This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain Criteria (RDoC) framework in a large transnosological population which cuts across DSM/ICD-10 disorder criteria categories. One thousand four …

Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders Read More »

Association of stress-related neural activity and baseline interleukin-6 plasma levels in healthy adults

Abstract Several studies suggest a link between acute changes in inflammatory parameters due to an endotoxin or (psychological) stressor and the brain’s stress response. The extent to which basal circulating levels of inflammatory markers are associated with the brain’s stress response has been hardly investigated so far. In the present study, baseline plasma levels of …

Association of stress-related neural activity and baseline interleukin-6 plasma levels in healthy adults Read More »

New publication out in Human Brain Mapping!

Abstract Accelerated maturation of brain parenchyma close to term-equivalent age leads to rapid changes in diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) metrics of neonatal brains, which can complicate the evaluation and interpretation of these scans. In this study, we characterized the topography of age-related evolution of diffusion metrics in neonatal brains. We included …

New publication out in Human Brain Mapping! Read More »

Determinants of motivated behavior are linked to fatigue and its perturbation by SARS-CoV-2 vaccination

Abstract Background Fatigue has an adaptive function and serves as a temporary signal to rest and save energy often in response to immune activation. It may, however, also persist in a pathological condition incurring significant burden. While subjective symptoms and scientific consensus indicate that both physical and mental determinants of motivated behavior are affected in fatigue, …

Determinants of motivated behavior are linked to fatigue and its perturbation by SARS-CoV-2 vaccination Read More »

The contribution of sleep to the neuroendocrine regulation of rhythms in human leukocyte traffic

Abstract Twenty-four-hour rhythms in immune parameters and functions are robustly observed phenomena in biomedicine. Here, we summarize the important role of sleep and associated parameters on the neuroendocrine regulation of rhythmic immune cell traffic to different compartments, with a focus on human leukocyte subsets. Blood counts of “stress leukocytes” such as neutrophils, natural killer cells, …

The contribution of sleep to the neuroendocrine regulation of rhythms in human leukocyte traffic Read More »

Scroll to Top