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Study protocol of the ASD-Net, the German research consortium for the study of Autism Spectrum Disorder across the lifespan: from a better etiological understanding, through valid diagnosis, to more effective health care
Abstract Background: Autism Spectrum Disorder (ASD) is a severe, lifelong neurodevelopmental disorder with early onset that places a heavy burden on affected individuals and their families. …
Laugh or cringe? Common and distinct processes of reward-based schadenfreude and empathy-based fremdscham
Abstract Witnessing others’ plights can be funny for observers, but may also trigger one to empathically cringe with the victim of the predicament. In the …
Reward: From basic reinforcers to anticipation of social cues
Abstract Reward processing plays a major role in goal-directed behavior and motivation. On the neural level, it is mediated by a complex network of brain …
Mechanisms of hemispheric lateralization: A replication study
Abstract It has been shown, using functional magnetic resonance imaging (fMRI), that hemispheric lateralization of brain activity depends on the requirements of the cognitive task …
Clinical trial of modulatory effects of oxytocin treatment on higher-order social cognition in autism spectrum disorder: a randomized, placebo-controlled, double-blind and crossover trial
Abstract Background: Autism spectrum disorders are neurodevelopmental conditions with severe impairments in social communication and interaction. Pioneering research suggests that oxytocin can improve motivation, cognition and …
Mindfulness meditation regulates anterior insula activity during empathy for social pain
Abstract Mindfulness has been shown to reduce stress, promote health, and well-being, as well as to increase compassionate behavior toward others. It reduces distress to …
Neural correlates of naturalistic social cognition: brain-behavior relationships in healthy adults
Abstract Being able to infer the thoughts, feelings and intentions of those around us is indispensable in order to function in a social world. Despite …
Handedness is related to neural mechanisms underlying hemispheric lateralization of face processing
Abstract While the right-hemispheric lateralization of the face perception network is well established, recent evidence suggests that handedness affects the cerebral lateralization of face processing …
Fronto-insula network activity explains emotional dysfunctions in juvenile myoclonic epilepsy: combined evidence from pupillometry and fMRI
Abstract Emotional instability, difficulties in social adjustment, and disinhibited behavior are the most common symptoms of the psychiatric comorbidities in juvenile myoclonic epilepsy (JME). This …
Neural pathways of embarrassment and their modulation by social anxiety
Abstract While being in the center of attention and exposed to other’s evaluations humans are prone to experience embarrassment. To characterize the neural underpinnings of …
Journal impact factor shapes scientists’ reward signal in the prospect of publication
Abstract The incentive structure of a scientist’s life is increasingly mimicking economic principles. While intensely criticized, the journal impact factor (JIF) has taken a role …
Neuronal pathways of embarrassment
Abstract Who has not already experienced the unpleasant feeling, when, for example, you were called to the board in school and could not answer the …
Effects of smoking cessation on presynaptic dopamine function of addicted male smokers
Abstract Background: There is evidence of abnormal cerebral dopamine transmission in nicotine-dependent smokers, but it is unclear whether dopaminergic abnormalities are due to acute nicotine abuse …
Mechanisms of hemispheric lateralization: Asymmetric interhemispheric recruitment in the face perception network
Abstract Perceiving human faces constitutes a fundamental ability of the human mind, integrating a wealth of information essential for social interactions in everyday life. Neuroimaging …
When your friends make you cringe: social closeness modulates vicarious embarrassment-related neural activity
Abstract Social closeness is a potent moderator of vicarious affect and specifically vicarious embarrassment. The neural pathways of how social closeness to another person affects …
Test-retest reliability of effective connectivity in the face perception network
Abstract Computational approaches have great potential for moving neuroscience toward mechanistic models of the functional integration among brain regions. Dynamic causal modeling (DCM) offers a …
Mentalizing and the role of the posterior superior temporal sulcus in sharing others’ embarrassment
Abstract The experience of embarrassment provides a highly salient cue for the human moral apparatus. Interestingly, people also experience embarrassment on behalf of others’ inappropriate …
Test-retest reliability of dynamic causal modeling for fMRI
Abstract Dynamic causal modeling (DCM) is a Bayesian framework for inferring effective connectivity among brain regions from neuroimaging data. While the validity of DCM has …
Evidence from pupillometry and fMRI indicates reduced neural response during vicarious social pain but not physical pain in autism
Abstract Autism spectrum disorder (ASD) is characterized by substantial social deficits. The notion that dysfunctions in neural circuits involved in sharing another’s affect explain these …
Association of rs1006737 in CACNA1C with alterations in prefrontal activation and fronto-hippocampal connectivity
Abstract Background: Genome-wide association studies have identified the rs1006737 single nucleotide polymorphism (SNP) in the CACNA1C gene as a susceptibility locus for schizophrenia and bipolar disorder. …