bioRxiv

Neurocomputational mechanisms underlying maladaptive self-belief formation in depression

Abstract A core symptom of major depression is maladaptive self-beliefs. These are perpetuated by negatively biased feedback processing. Understanding the neurocomputational mechanisms of biased belief updating may help to counteract maladaptive beliefs. The present study uses functional neuroimaging to examine neural activity associated with prediction error-based learning in depression and healthy controls. We hypothesized that […]

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Altered physiological, affective, and functional connectivity responses to acute stress in patients with alcohol use disorder

Abstract Background There is evidence that the processing of acute stress is altered in alcohol use disorder (AUD), but little is known about how this is manifested simultaneously across different stress parameters and which neural processes are involved. The present study examined physiological and affective responses to stress and functional connectivity in AUD. Methods Salivary

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Neurocomputational mechanisms of affected beliefs

Abstract The feedback people receive on their behavior shapes the process of belief formation and self-efficacy in mastering a given task. The neural and computational mechanisms of how the subjective value of these beliefs and corresponding affect bias the learning process are yet unclear. Here we investigate this question during learning of self-efficacy beliefs using

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