Publications

The Human Affectome

Abstract Over the last decades, the interdisciplinary field of the affective sciences has seen proliferation rather than integration of theoretical perspectives. This is due to differences in metaphysical and mechanistic assumptions about human affective phenomena (what they are and how they work) which, shaped by academic motivations and values, have determined the affective constructs and […]

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Rethink funding by putting the lottery first

Rethink funding Researchers propose a new way to restructure grant allocation, promoting inclusivity, innovation, and cost reduction. LÜBECK UNIVERSITY, Germany – The allocation process of funding to researchers is far from optimal. A recent project of the Open Science Initiative at the University of Lübeck (Germany) has put forward a new proposal to challenge and

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On the potentials of interaction breakdowns for HRI

Abstract How do we switch between “playing along” and treating robots as technical agents? We propose interaction breakdowns to help solve this “social artifact puzzle”: Breaks cause changes from fluid interaction to explicit reasoning and interaction with the raw artifact. These changes are closely linked to understanding the technical architecture and could be used to

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Individual differences in resilience to stress are associated with affective flexibility

Abstract Cognitive flexibility is frequently linked to resilience because of its important contribution to stress regulation. In this context, particularly affective flexibility, defined as the ability to flexibly attend and disengage from affective information, may play a significant role. In the present study, the relationship of cognitive and affective flexibility and resilience was examined in

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Neurocomputational mechanisms of affected beliefs

Abstract The feedback people receive on their behavior shapes the process of belief formation and self-efficacy in mastering a particular task. However, the neural and computational mechanisms of how the subjective value of self-efficacy beliefs, and the corresponding affect, influence the learning process remain unclear. We investigated these mechanisms during self-efficacy belief formation using fMRI,

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Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula

Abstract Based on neuroimaging data, the insula is considered important for people to empathize with the pain of others. Here we present intracranial electroencephalographic (iEEG) recordings and single-cell recordings from the human insulae while 7 epilepsy patients rated the intensity of a woman’s painful experiences seen in short movie clips. Pain had to be deduced

Intracranial human recordings reveal association between neural activity and perceived intensity for the pain of others in the insula Read More »

The (un)learning of social functions and its significance for mental health

Abstract Social interactions are dynamic, context-dependent, and reciprocal events that influence prospective strategies and require constant practice and adaptation. This complexity of social interactions creates several research challenges. We propose a new framework encouraging future research to investigate not only individual differences in capacities relevant for social functioning and their underlying mechanisms, but also the

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Neural correlates of affective task switching and asymmetric affective task switching costs

Abstract The control of emotions is of potentially great clinical relevance. Accordingly, there has been increasing interest in understanding the cognitive mechanisms underlying the ability to switch efficiently between the processing of affective and non-affective information. Reports of asymmetrically increased switch costs when switching towards the more salient emotion task indicate specific demands in the

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Dysregulated autoantibodies targeting vaso- and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity

Abstract Most patients with Post COVID Syndrome (PCS) present with a plethora of symptoms without clear evidence of organ dysfunction. A subset of them fulfills diagnostic criteria of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Symptom severity of ME/CFS correlates with natural regulatory autoantibody (AAB) levels targeting several G-protein coupled receptors (GPCR). In this exploratory study, we

Dysregulated autoantibodies targeting vaso- and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity Read More »

Age-dependent white matter microstructural disintegrity in autism spectrum disorder

Abstract There has been increasing evidence of White Matter (WM) microstructural disintegrity and connectome disruption in Autism Spectrum Disorder (ASD). We evaluated the effects of age on WM microstructure by examining Diffusion Tensor Imaging (DTI) metrics and connectome Edge Density (ED) in a large dataset of ASD and control patients from different age cohorts. N = 583

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