Sören Krach

Assessment of reward-related brain function after a single-dose of oxytocin in autism: a randomized controlled trial

2021, Clinical, Hormones/Neuromodulators, Social Reward /

Background Autism spectrum disorder (ASD) is characterized by difficulties in social communication and interaction, which have been related to atypical neural processing of rewards, especially in the social domain. Since intranasal oxytocin has been shown to modulate activation of the brain’s reward circuit, oxytocin might ameliorate the processing of social rewards in ASD and thus […]

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A psychological perspective on vicarious embarrassment and shame in the context of cringe humor

2021, Social Emotions /

Abstract Cringe humor combines the seemingly opposite emotional experiences of amusement and embarrassment due to others’ transgressions of norms. Psychological theories and empirical studies on these emotional reactions in response to others’ transgressions of social norms have mostly focused on embarrassment and shame. Here, we build on this literature, aiming to present a novel perspective

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Rejection of BMBF-application “LoCODe”

Fails /

Long-COVID depression (LoCODe) Today we received a rejection of our BMBF-application “LoCODe”.   Topic: i) To understand and characterise long-COVID depression (LoCODe) clinically and via biomarkers that discern depressive patients with and without prior SARS-CoV-2 infection. ii) To enable stratified therapeutic observations and targeted interventional trials. iii) To discern adaptational or incidental depression from a post infectious

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Editorial: The Different Faces of Sickness

2021, Clinical /

Editorial on the Research Topic: The Different Faces of Sickness   Sickness not only includes symptoms that classically define an infection (e.g., fever, nausea, headache), but also comes along with profound neurobehavioral consequences for the infected individual. These include anhedonia, anorexia, pain, lethargy, fatigue, sleepiness, and social withdrawal, and are collectively called “sickness behavior” (1).

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Reduced frontal cortical tracking of conflict between self-beneficial versus prosocial motives in Narcissistic Personality Disorder

2021, Clinical, Social Cognition /

Abstract Abstract Narcissistic Personality Disorder (NPD) entails severe impairments in interpersonal functioning that are likely driven by self-beneficial and exploitative behavior. Here, we investigate the underlying motivational and neural mechanisms of prosocial decision-making by experimentally manipulating motivational conflict between self- beneficial and prosocial incentives. One group of patients diagnosed with NPD and a group of

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New publication on Neural processing in Narcissistic Personality Disorder out in NeuroImage: Clinical!

Science /

Reduced Frontal Cortical Tracking of Conflict between Self-Beneficial versus Prosocial Motives in Narcissistic Personality Disorder   Thanks to the great collaboration with Stefan Roepke and Aline Vater at the Universitätsmedizin Charité as well as Björn Schott at the Leibniz Institute for Neurobiology in Magdeburg we are happy to announce the publication of our first paper

New publication on Neural processing in Narcissistic Personality Disorder out in NeuroImage: Clinical! Read More »

Self-beneficial belief updating as a coping mechanism for stress-induced negative affect

2021, Hormones/Neuromodulators, Social Learning, Social Reward /

Abstract Being confronted with social-evaluative stress elicits a physiological and a psychological stress response. This calls for regulatory processes to manage negative affect and maintain self-related optimistic beliefs. The aim of the current study was to investigate the affect-regulating potential of self-related updating of ability beliefs after exposure to social-evaluative stress, in comparison to non-social

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New publication on self-related learning processes out in Scientific Reports!

Science /

Self-beneficial belief updating as a coping mechanism for stress-induced negative affect.   Very cool new computational modeling paper by Nora Czekalla et al. on how stress/affect are better recovered depending on the way people integrate novel information about themselves into their self-concept. With this new data we replicate and extend earlier findings of a negativity

New publication on self-related learning processes out in Scientific Reports! Read More »

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